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Whooping cough: Scientists sequence strain but face challenges in tracking spread

Author
RNZ,
Publish Date
Fri, 7 Apr 2023, 1:55pm
Newly finished sequencing on a sample shows the vaccine is likely to work against the detected strain. Photo / File
Newly finished sequencing on a sample shows the vaccine is likely to work against the detected strain. Photo / File

Whooping cough: Scientists sequence strain but face challenges in tracking spread

Author
RNZ,
Publish Date
Fri, 7 Apr 2023, 1:55pm

A strain of whooping cough spreading has been sequenced, but scientists are finding it hard to track where it has come from.

Public health officials were聽urgently trying to sequence the strain聽to see if it is unusually deadly after聽three babies died from the disease, also known as pertussis, this year.

Environmental Science and Research bioinformatics and genomics senior science lead Joep de Ligt told RNZ a sample from a young child showed the strain was likely covered by the current vaccine, according to newly finished sequencing.

鈥淭he vaccine will still work based on the typing that we鈥檝e done. So you can do antigen typing. So that鈥檚 part of the bacteria that is seen by the immune system, and we can then see if that is part of the current vaccine that is offered... For the sample we have analysed, we could see that it is likely covered.鈥

The disease was 鈥渜uite hard to get a culture from鈥 and it was therefore 鈥渜uite hard鈥 to trace its spread, de Ligt said.

鈥淪o there鈥檚 not historic data available, or at least not a lot. So it鈥檚 not like with Covid that we could say that it had come in on a boat or something like that.鈥

Vaccination for pregnant women: 鈥榃e鈥檝e really, really dropped the ball badly鈥

Meanwhile, Te Whatu Ora has written to doctors and midwives this week, asking them to prioritise vaccinating pregnant women to protect babies.

It also released a report saying some immunisation rates for under-fives were 鈥渄ire鈥.

University of Auckland vaccinologist Helen Petousis-Harris told RNZ dwindling child immunisation rates against diseases like whooping cough were 鈥渞eally unfortunate鈥.

Vaccinologist Helen Petousis-Harris says there are moves to address low rates of pregnant women being vaccinated against whooping cough. Photo /  RNZVaccinologist Helen Petousis-Harris says there are moves to address low rates of pregnant women being vaccinated against whooping cough. Photo / RNZ

鈥淚t鈥檚 a real worry. Because this winter, we could see some real resurgence in some diseases that actually are preventable.鈥

Petousis-Harris believed Aotearoa had not taken whooping cough vaccination drives seriously enough.

鈥淚 think we鈥檝e really, really dropped the ball badly on it. But over a long period of time, actually. So it鈥檚 not just recent, but it鈥檚 across time.

鈥淲e started this programme of vaccinating pregnant women back, it was about 10 years ago now. We鈥檝e never really achieved very good coverage and that鈥檚 because there wasn鈥檛 enough effort that went in across the board to get that coverage up.

鈥淭here are now moves, and big, really strong moves, to try and improve it and address it. But I think the most important message is if you鈥檙e pregnant, or know somebody pregnant, make sure they鈥檝e had this booster because this disease is out there. It can be lethal in small babies.鈥

It was now an 鈥渆mergency鈥 situation, Petousis-Harris said.

She hoped 鈥渨e can have some good long-term solutions and won鈥檛 see this happen again in the future, but at the moment, we鈥檝e got a long way to go, before we can consider this problem solved鈥.

She also acknowledged it was a difficult time to ramp up vaccinations when health services were 鈥渦nder the pump鈥 - coping with other winter illnesses spreading, Covid, and staffing problems.

鈥淭he workforce shortage is one of the big issues... People [having difficulties] being able to access the services has become a growing problem.鈥

-Sam Olley and Felix Walton,聽RNZ

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